High Potency Linear Polyethylenimine - A New Cationic Polymer
Polysciences, Inc. is pleased to announce the availability of a nearly fully hydrolyzed linear polyethylenimine with longer contiguous ethyleneimine segments. Polyethylenimine "Max" is built from the same polymer backbone (MW 25,000) as the popular linear polyethylenimine. Despite the fact N-deacylation reactions are notoriously difficult, our new linear polyethylenimine material is believed to contain more than 11% additional free (protonatable) nitrogens than our original linear polyethylenimine material (Cat. # 23966). Estimates¹ of the average number of repeating ethyleneimine units ranges to around 581 segment, resulting in dramatically increased lengths of protonatable nitrogens. Our material is supplied as a hydrochloride salt for ease of handling but may be converted into the free amine form by neutralization with base.
References:
(1) See Klibanov etc. al. Proceedings of the National Academy of Sciences, vol. 102, no. 16, 5679-5684 (2005). Published on-line prior to printing on 4/11/05
Properties
Appearance: White to off-white free flowing solid
Molecular Weight (Mw): Nominal Mw 40,000 (Comparable to Cat. No. 23966 - Polyethylenimine, Linear, MW 25,000 which is not in the hydrochloride salt form)
Chemical Structure: Hydrochloride salt of linear polyethylenimine
Solubility: Highly water soluble in hydrochloride salt form
Insoluble in: Common organic solvents (ethanol, acetone, tetrahydrofuran)
Soluble in: Cold and room temperature water
Elemental Analysis of Polyethylenimine "Max"
Theoretical Carbon 30.20 Theoretical Nitrogen 17.62 Theoretical Chloride 44.57
Found Carbon 29.92 Found Nitrogen 17.35 Found Chloride 44.25