Divinyl Adipate

Divinyl adipate is a reactive double vinyl ester that can be used as a crosslinker to crosslink hydroxyl containing polymers. It has been used to synthesize biodegradable hydrogels and other crosslinked biodegradable polymers.

For use as a linker to synthesize biodegradable block copolymers of poly[(R)-3-hydroxybutyrate] diol and poly[(R)-3-hydroxyoctanoate] diol, see:

“Enzyme-Catalyzed Polycondensation of Polyester Macrodiols with Divinyl Adipate: A Green Method for the Preparation of Thermoplastic Block Copolyesters”  Dai, S.; et al. Biomacromolecules, 2009, 10 (12), pp 3176–3181

For use as a crosslinker to make biodegradable glycol chitosan hydrogels, see:

“Facile Preparation of Biodegradable Glycol Chitosan Hydrogels Using Divinyladipate as a Crosslinker”  Kim, B.S.; et al. Macromolecular Research, Vol. 17, No. 10, pp 734-738 (2009)