Grocott Methenamine Silver Stain (GMS) for Fungus & PCP
Room Temperature & Microwave Kit

Chromic acid oxidation forms aldehydes from fungal cell wall polysaccharide components, which are subsequently demonstrated by reduction of an alkaline hexamine-silver complex. The reaction may be compared to that of the periodic acid Schiff reaction.

Grocott's alkaline hexamine-silver solution allows silver ions upon reduction, to appear dark or black, also known as "argentaffin reaction" the ability of a silver complex solution to blacken a tissue element without the need of a reducing bath.