Paraformaldehyde depolymerizes in water to formaldehyde solution yielding consistent quality fixative solutions. To achieve a strong solution, raise the temperature of the water to 60ºC then add sodium hydroxide solution dropwise.
Karnovsky, M. J. A Formaldehyde-Glutaraldehyde Fixative of High Osmolality for Use in Electron Microscopy. The Journal of Cell Biology 27, 137A (1965).
- Flammable solid
- Glove, chemical goggles & fume hood
- Store at room temperature