Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).1 The control of these properties makes PLGA especially well suited for applications where medical devices are only needed for weeks (e.g. drug delivery). 2-3
Acid-terminated PLGA allows for easy conjugation to drugs with nucleophilic functionalities.4Synonyms: PDLGA, PLGA, DL-PLGA
SPECIFICATIONSFTIR: conforms Inherent Viscosity (ηinh): 0.15 - 0.25 dL/g (25°C; CH3Cl) Acid Number: ≥ 6 (mg KOH)/g LA/GA : 20-30/70-80 mol % (NMR)
PROPERTIESViscosity Molecular Weight (Mη): 10,000 - 18,000 Glass Transition Temp. (Tg): 55-60°C  Soluble in: dichloromethane (DCM), tetrahydrofuran (THF), ethyl acetate, acetone
- Irritant , Hygroscopic
- Exercise normal care
- Protect from moisture. Store at -20°C.