目录产品

Poly(DL-lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications. In comparison to poly(L-lactide) (PLLA), PLGA offers control over degredation rate and reduced glass transition temperatures (by increasing glycolide content).¹ The control of these properties makes PLGA especially well suited for applications where medical devices are only needed for weeks (e.g. drug delivery).

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Acid-terminated PLGA allows for easy conjugation to drugs with nucleophilic functionalities.⁴

Synonyms: PDLGA, PLGA, DL-PLGA

SPECIFICATIONS

FTIR: conforms
Inherent Viscosity (η_inh): 0.15 - 0.25 dL/g (25°C; CH₃Cl)
Acid Number: ≥ 6 (mg KOH)/g
LA/GA : 20-30/70-80 mol % (NMR)

PROPERTIES

Viscosity Molecular Weight (M_η): 10,000 - 18,000
Glass Transition Temp. (T_g): 55-60°C [1]
Soluble in: dichloromethane (DCM), tetrahydrofuran (THF), ethyl acetate, acetone