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Granular Blue (GB) Dihydrochloride

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26273-1 1 mg
$91.00
In Stock: 10
26273-5 5 mg
$364.00
In Stock: 2

Description

Granular Blue (GB) is a fluorescent retrograde tracer used in experimental studies of the peripheral nervous system to determine the number and origin of neurons projecting to a specific area.

In rats, GB is effectively transported over long distances to produce blue fluorescent labeling of neuronal cytoplasm in cell bodies and proximal dendrites. It also produces an accumulation of silver-blue granules in cytoplasm.

Excitation: 365 nm
Emission: 410 nm
CAS#:
55453-00-4
Formula:

C22H19N5O · 2HCl


Molecular Weight:
442.4
Soluble In:
Water
Appearance:
Powder

Reference(s):

Liang, Y.-X. et al. Uptake of Retrograde Tracers by Intact Optic Nerve Axons: A New Way to Label Retinal Ganglion Cells. PLOS ONE 10, e0128718 (2015). doi:10.1371/journal.pone.0128718

Wouterlood, F. G. A survey of current neuroanatomical tracing techniques. Neural Tracing Methods: Tracing Neurons and Their Connection. Neuromethods 92, 1–49 (2014). doi:10.1007/978-1-4939-1963-5_1

Distler, C., Mustari, M. J. & Hoffmann, K.-P. Cortical projections to the nucleus of the optic tract and dorsal terminal nucleus and to the dorsolateral pontine nucleus in macaques: A dual retrograde tracing study. The Journal of Comparative Neurology 444, 144–158 (2002). doi:10.1002/cne.10127

Harmann, P. A., Carlton, S. M. & Willis, W. D. Collaterals of spinothalamic tract cells to the periaqueductal gray: a fluorescent double-labeling study in the rat. Brain Research 441, 87–97 (1988). doi:10.1016/0006-8993(88)91386-8

Kuypers, H.G.J.M., Huisman, A.M. Fluorescent neuronal tracersAdv. Cellular. Neurobiol. 5, 307-340 (1984).


Storage:
Store at room temperature

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