Linear polyethylenimine (PEI) is a high-charge cationic polymer that readily binds highly anionic substrates. Industrially, linear PEI can improve the appearance of negatively charged dyes by modulating their properties and improving their adherence to surfaces. In research, PEI readily binds to DNA and other negatively charged biological molecules, making it one of the most efficient vector carriers available.
Product contains 7-11% of the acylated amine (N-propionyl) from isomerization-polymerization of 2-ethyl-2-oxazoline followed by acid-hydrolysis of resulting N-propionyl-PEI. For fully deacylated PEI, see Polyethylenimine HCl MAX, Linear, Mw 160,000 (PEI MAX 160000; Catalog # 25439)
- 9002-98-6, 26913-06-4
- Molecular Weight:
- Melting Point:
- Soluble In:
- hot water, cold water at low pH, methanol, and ethanol
Insoluble In:Benzene, ethyl ether, acetone and cold water.
- White to tan solid
Thomas M, Lu JJ, Ge Q, Zhang C, Chen J, Klibanov AM. (2005). Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung. Proc Natl Acad Sci U S A. 102(16):5679-84.
- Gloves & fume hood
- Store at room temperature