TDMAC (Tridodecylmethylammonium chloride)

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Catalog No. Packaging Size Price Quantity
01595-1 1 g
01595-5 5 g
01595-25 25 g
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Tridodecylmethylammonium chloride (TDMAC) is a chloride ion-selective solvent polymeric membrane electrodes component. The ion-selective electrodes (ISEs; membrane electrodes) are electrochemical sensors useful in various analytical applications. TDMAC used as a polymer membrane-based electrode exhibits significant potentiometric response to heparin in the clinically relevant concentration range.

Additionally, TDMAC-heparin complexes are used as an antithrombogenic coating for catheters and tubing from which heparin is released slowly via an ion-exchange process. (See Polysciences catalog products 03813 and 03921 for TDMAC-heparin (Tridodecylmethylammonium heparinate) solutions).

[CH3(CH2)11]3N+CH3 Cl-

Molecular Weight:
Melting Point:
105-114° C

Ibrahim H.A. Badr, Gamal A. Saleh, Sayed M. Sayed and Deena A.M. Nour El-Deen (2014) A novel membrane sensor for batch and flow injection potentiometric determination of cefazolin sodium in pharmaceutical preparations. Int. J. Electrochem. Sci., 9 (2014) 1621 - 1636

Sjöberg, P., Bobacka, J., Lewenstam, A., & Ivaska, A. (1999). All-Solid-State Chloride-Selective Electrode Based on Poly(3-octylthiophene) and Tridodecylmethylammonium Chloride. Electroanalysis, 11(10-11), 821–824.;2-F

Kim, Wantae, et al. Sol-gel method for the matrix of chloride-selective membranes doped with tridodecylmethylammonium chloride.Analytical Chemistry 69.1 (1997): 95-98.

Ma, S. C., Yang, V. C. & Meyerhoff, M. E. Heparin-responsive electrochemical sensor: a preliminary study. Analytical Chemistry 64, 694–697 (1992). doi:10.1021/ac00030a023

Kamal, G. D., Pfaller, M. A., Rempe, L. E., & Jebson, P. J. (1991). Reduced intravascular catheter infection by antibiotic bonding. A prospective, randomized, controlled trial . JAMA, 265(18), 2364–2368.

Wegmann, D., Weiss, H., Ammann, D., Morf, W. E., Pretsch, E., Sugahara, K., & Simon, W. (1984). Anion-selective liquid membrane electrodes based on lipophilic quaternary ammonium compounds. Microchimica Acta, 84(1), 1–16. doi:10.1007/BF01204153

Harvey, R. A., Alcid, D. V, & Greco, R. S. (1982). Antibiotic bonding to polytetrafluoroethylene with tridodecylmethylammonium chloride.Surgery, 92(3), 504–512.

Hartman, K., Luterotti, S., Osswald, H. F., Oehme, M., Meier, P. C., Ammann, D., & Simon, W. (1978). Chloride-selective liquid-membrane electrodes based on lipophilic methyl-tri-N-alkyl-ammonium compounds and their applicability to blood serum measurements. Microchimica Acta, 70(3), 235–246. doi:10.1007/BF01201614

Irritant , Hygroscopic
Gloves & chemical goggles
Protect from moisture;Store at room temperature

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