Poly(DL-lactide) (PDLLA) is an ubiquitous biodegradable polymer. It is typically used to fabricate medical devices that predictably degrade over months in physiological conditions. The well-researched release profile also allows for drug-release functionalization with calculable results.1 Owing to its extensive history, PDLLA is one of the most understood and affordable biodegradable polymers for medical devices today.
Synonyms: PDLLA, DL-PLA, PDLA
1. Middleton, J. C. & Tipton, A. J. Synthetic biodegradable polymers as orthopedic devices. Biomaterials 21, 2335–2346 (2000). doi:10.1016/S0142-9612(00)00101-0
Inherent Viscosity (ηinh): 0.10 - 0.30 dL/g (25°C; CHCl3, 1.8 g/dL)
Soluble in: dichloromethane (DCM), tetrahydrofuran (THF), ethyl acetate, acetone