HOPE^® - Formalin-free fixation technique for molecular pathology and research!

Tissue conservation using the new HOPE^®-technique provides paraffin embedded tissue blocks with native structure of the macro-molecules (protein, DNA, RNA) in the tissue.

HOPE^® - Formalin-free fixation technique for molecular pathology and research!

Tissue conservation using the new HOPE^®-technique provides paraffin embedded tissue blocks with native structure of the macro-molecules (protein, DNA, RNA) in the tissue.

Guanidine Thiocyanate also has the added benefit of being a chaotropic agent. This feature allows it to decrease the action of hydrogen bonds in water as well as disrupts intramolecular interactions within proteins and other macromolecules – further increasing solubility of unwanted cellular components.

Hydroxynapthol Blue is suitable for calcium determinations.