Sterols
  1. Cholesterol
    Cholesterol
    Catalog Number 26436

    Cholesterol is a naturally occurring sterol lipid that is a receiving growing emphasis in the bioprocessing space for its ability to improve DNA transfection efficiency by reducing the adherence of serum proteins to lipopolyplexes and increasing fusion with cellular membranes.

  2. Beta-sitosterol
    Beta-sitosterol
    Catalog Number 14495

    Beta-sitosterol is a naturally occurring sterol lipid that is growing in the bioprocessing space for its ability to improve mRNA transfection efficiency.

  3. Stigmasterol
    Stigmasterol
    Catalog Number 14497

    Stigmasterol is a naturally occurring phytosterol lipid that is growing in the bioprocessing space for its ability to improve lipid nanoparticle (LNP)-based mRNA transfection efficiency.

  4. β-Sitosteryl hemisuccinate (β-STEMS)

    β-Sitosteryl hemisuccinate is a β-sitosterol derivative that has been shown to have cholesterol lowering effects.

  5. Cholesteryl Hemisuccinate (CHEMS)

    Cholesteryl hemisuccinate (CHEMS) is a cholesterol derivate that is responsive to changes in pH.

  6. Stigmasteryl hemisuccinate (STEMS)

    Stigmasteryl hemisuccinate (STEMS) is a stigmasterol derivative that is responsive to changes in pH.

  7. desmosterol
    desmosterol
    Catalog Number 14522
    Desmosterol is a sterol lipid with a backbone similar to cholesterol. It is the precursor to cholesterol in the Bloch biosynthesis pathway. It is known to be a regulator of lipid metabolism.
  8. lathosterol
    lathosterol
    Catalog Number 14523
    Lathosterol is a precursor in the cholesterol synthesis pathway. Lathosterol can be used as a biomarker of excess cholesterol production as lathosterol levels in serum corresponds with cholesterol synthesis.
  9. sitostanol
    sitostanol
    Catalog Number 14524
    Sitostanol is a saturated plant sterol that can be used to lower serum cholesterol.
  10. Brassicasterol
    Brassicasterol
    Catalog Number 14525
    Brassicasterol is a phytosterol that can be used as a biomarker to detect the presence of marine algal matter.
  11. Fucosterol
    Fucosterol
    Catalog Number 14510
    Fucosterol is a plant sterol that has antioxidant and antiinflammatory properties. Inclusion of fucosterol in lipid nanoparticle (LNP) formulations has been shown to increase transfection efficiency rates both in cell cultures and in vivo, leading to particular interest in the use of the lipid in mRNA vaccine development.
  12. Campesterol
    Campesterol
    Catalog Number 14511
    Campesterol is a phytosterol and an agonist of liver X receptors, which are involved in the transcriptional control of lipid metabolism. Inclusion of campesterol in lipid nanoparticle (LNP) formulations has been shown to increase transfection efficiency rates both in cell cultures and in vivo, leading to particular interest in the use of the lipid in mRNA vaccine development.
  13. BODIPY-Cholesterol
    BODIPY-Cholesterol
    Catalog Number 14526
    Bodipy-Cholesterol is cholesterol tagged with the fluorophore BODIPY. It can be used to monitor uptake in LNP uptake in cells. It has an ex/em of 480 nm/508 nm.
  14. 7-dehydrocholesterol (high purity)
    7-dehydrocholesterol is an immediate precursor of cholesterol in the cholesterol biosynthesis pathway. It is also a provitamin that is converted to vitamin D3 by UVB light.
  15. Cholesterol Sulfate
    Cholesterol Sulfate
    Catalog Number 14535
    Cholesterol sulfate (sodium salt) is found in cell membranes. It affects lipid metabolism, stabilizes the cell membrane, and acts as a substrate for steroid synthesis. It can be used in the development of liposomes when studying the properties of cell membranes.
  16. 8-dehydro cholesterol
    8-dehydro cholesterol
    Catalog Number 14536
    8-dehydro cholesterol is an isomer of an immediate precursor of cholesterol (7-DHC) in the cholesterol biosynthesis pathway.
  17. Dehydroepiandrosterone (DHEA)
    DHEA is an endogenous steroid secreted by the adrenal gland. It is known to modulate a variety of cellular and nuclear receptors.
  18. Diosgenin
    Diosgenin
    Catalog Number 14538
    Diosgenin is a natural steroid that has anti-inflammatory, hypoglycemic, and pro-apoptotic properties.
  19. Cholesterol (plant-based)
    Cholesterol (plant-based)
    Catalog Number 14565
    Inquire for availability.
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