Synthesis and Purification Competencies

Polysciences Inc. has been an established supplier of specialty biomedical materials since 1961. Polysciences has partnered with innovative companies both large and small in the development of biodegradable polymers and microparticles for medical device and drug delivery applications. Polysciences currently develops and manufactures novel monomers and polymers for a range of applications including:

Cardiovascular – Device Coatings and Biodegradable Microspheres for Calibration

Ophthalmic – Specialty Monomers, Polymeric Coatings and Additives

Bioassay Systems – Surface Active Microparticles and Hydrogel Polymers

Our design / development and manufacturing capabilities include the following:

Monomer & Polymer Technologies

• Biodegradable polymers for controlled release of pharmaceuticals
• Synthetic polymers for medical device coatings and excipients for medical formulations
• Polymeric hydrogels
• UV absorbing monomers and polymers
• Ultra-pure specialty monomers for ocular polymer design
• Low ionic content polymers
• Fluorinated polymer compositions for hydrophobic and low surface energy applications
• Pressure polymers (e.g. PEVA, PEVOH and ethylene-acrylic polymers)
• Macroreticular resins with embedded functional groups
• PEG-ylated small molecules & block copolymers

Microsphere & Particle Technologies

• Uniform biodegradable polymeric microspheres and nanospheres (e.g. PLGA, PEG-lactic acid)
• Functionalized microparticles and nanoparticles for antibody coupling & diagnostic assay development
• Paramagnetic micro and nanospheres for medical diagnostics
• Uniform NIST polystyrene microspheres & nanospheres for instrument calibration
• Particle sizing and isolation technologies

Manufacturing Capabilities

• FDA registered facility (#2518071)
• ISO 13485:2016 Certification
• Class 100 (ISO 5) & Class 100,000 (ISO 8) clean rooms
• Strong regulatory expertise
• cGMP manufacturing
• Lab scale high pressure reactor for ethylene copolymer structure-property optimization
• Deep expertise in polymer chemistry and synthetic organic chemistry