HOPE^® - Formalin-free fixation technique for molecular pathology and research!

Tissue conservation using the new HOPE^®-technique provides paraffin embedded tissue blocks with native structure of the macro-molecules (protein, DNA, RNA) in the tissue.

Sulfonated triazine dye that can be immobilized on a support matrix and used for affinity chromatography of proteins. Also used for probing nucleotide binding sites in proteins. (Reactive blue 2)

¹H NMR and mass spectrometry data are consistent with the structure shown.

Used to stain DNA, RNA, and protein. Also useful for staining acid polysaccharides.

DNA stain blue

RNA stain bluish-purple

Protein stain red

Frameshift mutagenic standard for Ames test in Salmonella and E. Coli.

([6-Chloro-9-(3-[2-chloroethylamino]propylamino)-2-methoxyacridine] dihydrochloride; ICR 191 Acridine mutagen; Ames mutagen 191)

Useful in in vitro cell growth assays with possible applicability to a variety of problems in cellular pharmacology and biology.

Histochemical substrate for β-galactosidase.

X-gal

A cationic fluorescent dye which specifically binds to adenine-thymine-rich DNA. Applications include detection of nanogram quantities of DNA in cellular homogenates, and cytofluorometric determination of the DNA base content in human chromosomes. Available in bulk quantities for OEM users at significant savings.

λ max 342nm

Used in combination with methyl green for the selective and differential staining of nucleic acids. The pyronin Y stains RNA red, while the methyl green stains DNA green. The combined methyl green-pyronin Y stain is a useful histochemical reagent. Pyronin Y can also be used as a tracking dye for polyacrylamide gel electrophoresis.

λmax 552nm

DNA intercalating dye. A grade of acridine orange of exceptionally high purity, suitable for quantitative work. Free of inorganic salts. A specific stain for RNA, used as a 2% solution containing 1% lanthanum acetate in 15% acetic acid.

Polyene antibiotic fluorochrome for cholesterol determination. Used as an antifungal agent.

Cyanoditolyl tetrazolium chloride has been used to measure the redox activity of tumor cells. It has also been employed for direct epifluorescent microscopic enumeration of respiring bacteria in food samples and environmental samples, especially water samples.

(Food green 3). Sensitive stain for proteins in polyacrylamide gels. Especially suitable in isoelectric focusing. Also suitable for use as a cytological counterstain, and mammalian tissue stain for muscle and collagen.

λ max 622-626nm.

Protein stain for SDS gels. Used in dye binding techniques for protein quantification.

(Coomassie blue® G250; Brilliant blue G250; Acid blue 90)

λmax 610nm

Rapid acting and sensitive dye for SDS gels.

(Coomassie blue® R250; Brilliant blue R250; Acid blue 83)

λmax 588nm

Reduced ethidium bromide. A vital stain. Enters and stains living cells without cellular trauma.

Stable DNA stain.

Fluorescent chromosome stain. Recommended use is 10mg/ml for 2-10 minutes. This will vary based on section thickness.

(2’-[4-Hydroxyphenyl]-5-[4-methyl-1-piperazinyl]-2,5’-bi-1H-benzimidazole trihydrochloride pentahydrate; Hoechst 33258)

DNA intercalating dye. A grade of acridine orange of exceptionally high purity, suitable for quantitative work.

A metachromatic, cationic thiazine dye that is widely used in in vitro biological applications. It has also been used in techniques for DNAase detection.

λmax 626nm

Useful for staining RNA, oligodeoxynucleotides, proteins and glycosaminoglycans.

λ max 626nm.

Assay >60% anhydrous dye.

Electron microscopy stain.

HOPE^® - Formalin-free fixation technique for molecular pathology and research!

Tissue conservation using the new HOPE^®-technique provides paraffin embedded tissue blocks with native structure of the macro-molecules (protein, DNA, RNA) in the tissue.

Guanidine Thiocyanate also has the added benefit of being a chaotropic agent. This feature allows it to decrease the action of hydrogen bonds in water as well as disrupts intramolecular interactions within proteins and other macromolecules – further increasing solubility of unwanted cellular components.

Hydroxynapthol Blue is suitable for calcium determinations.

α-tocopherol, an isoform of vitamin E, is  a lipid soluble anti-oxidant.

Resiquimod is a TLR7/TLR8 synthetic agonist that can be used as a vaccine adjuvant to improve antigen-specific antibody production.

TDB is a glycolipid adjuvant and an immunomodulator that is used to develop non-phospholipid based liposomal-like nanoparticles.

FSL-1 is a synthetic lipoprotein and an agonist of the TLR2/TLR6 heterodimer which induces an innate immune response. 

Fast blue fluorescent tracer used in studies of peripheral nervous system to determine the number & origin of neurons projecting to specific area