Poly(Caprolactone-co-L-lactide), 85:15, IV 1.3 dL/g
CAS Number:
70524-20-8
Linear Formula:
(C6H10O2)m(C6H8O4)n
In stock
Poly(Caprolactone-co-L-lactide) (PCLLA) is a biodegradable and biocompatible copolymer that has a range of potential applications in the biomedical and pharmaceutical industries and is commonly used as a material for medical devices, 3D printed tissue engineering scaffolds, and drug delivery.
The biodegradation rate of PCLLA is influenced by monomer ratio and molecular weight. PCLLA is composed of the monomers caprolactone and L-lactide, with higher ratio of caprolactone resulting in a slower degradation rate due to it being more hydrophobic than L-lactide, and thus less susceptible to ester hydrolysis. Generally, a higher molecular weight also denotes a slower degradation rate.
We offer several PCLLA products of varying monomer ratios and molecular weights.
Shipping Requirements:
Dry Ice
Synonyms/Acronyms:
PCL/PLA
PCL-co-Lactide Copolymer
PCL and Lactide Copolymer
PCLLA
Viscosity:
~1.6 dL/g [i.v.]
Appearance:
White to off-white solid
Molecular Weight:
-
Biodegradation Time:
~ Months
1. Fabienne Faÿ, Estelle Renard, Valérie Langlois, Isabelle Linossier, Karine Vallée-Rehel, Development of poly(ε-caprolactone-co-l-lactide) and poly(ε-caprolactone-co-δ-valerolactone) as new degradable binder used for antifouling paint, European Polymer Journal, Volume 43, Issue 11,
2007, Pages 4800-4813, ISSN 0014-3057. https://doi.org/10.1016/j.eurpolymj.2007.07.045.
2. Jiang, Zhiqiang, Xianmo Deng, and Jianyuan Hao. "Thermogelling hydrogels of poly (ε‐caprolactone‐co‐D, L‐lactide)–poly (ethylene glycol)–poly (ε‐caprolactone‐co‐D, L‐lactide) and poly (ε‐caprolactone‐co‐L‐lactide)–poly (ethylene glycol)–poly (ε‐caprolactone‐co‐L‐lactide) aqueous solutions." Journal of Polymer Science Part A: Polymer Chemistry 45.17 (2007): 4091-4099. https://doi.org/10.1002/pola.22222
3. Fernández, Jorge, Agustin Etxeberria, and Jose-Ramon Sarasua. "In vitro degradation studies and mechanical behavior of poly (ε-caprolactone-co-δ-valerolactone) and poly (ε-caprolactone-co-L-lactide) with random and semi-alternating chain microstructures." European Polymer Journal 71 (2015): 585-595. https://doi.org/10.1016/j.eurpolymj.2015.09.004
Hazards:
Harmless - use normal precautions; Hygroscopic
Handling:
Gloves & fume hood
Storage:
Protect from moisture. Store at -20°C.
