Bielschowsky Stain Kit

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Catalog Number Unit Size Price QTY
25994-250 1 kit (250mL)
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The Bielschowsky Stain is a very useful method in detecting the twist and clumping of neurons in the brain, otherwise known as, neurofibrillary tangles and senile plaques, which are signs of the Alzheimer’s disease. The Bielschowsky stain, along with other diagnostic test, can assist scientist and researchers in the mission for finding a cure for this disease of memory loss. We recommend kit is used on formalin fixed paraffin embedded tissue sections of 8-10 microns.

250 ml Kit Components (stains up to 64 slides):
  • 10% Silver Nitrate Solution (250 ml; SOLN A)
  • Ammonium Hydroxide, concentrate (125 ml; SOLN B)
  • Developer Stock Solution (5 ml; SOLN C)
  • 1% Ammonium Hydroxide Solution (250 ml; SOLN D)
  • 5% Sodium Thiosulfate (250 ml; SOLN E)

  • Results:
  • Neurofibrillary tangles and senile plaques - black
  • Axons - black
  • Nerve fibers - brown to black
  • Background - yellow to brown
  • Marquié, M. et al. Pathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies. Annals of Neurology 81, 117–128 (2017). doi:10.1002/ana.24844

    Bancroft, J. D. & Gamble, M. Theory and practice of histological techniques. (Churchill Livingstone/Elsevier, 2008).