Cholesteryl Hemisuccinate (CHEMS)
CAS Number:
1510-21-0
Molecular Formula:
C31H50O4
In stock
Cholesteryl hemisuccinate (CHEMS) is a cholesterol derivate that is responsive to changes in pH. When incorporated in lipid bilayer membranes, it provides membrane stabilization activity, but when exposed to acidic environments it results in a break of the lipid membrane which facilitates drug release. It can also be used in conjunction with DOPE to improve transfection efficiency.
SYNONYM: CHEMS
Application(s):
drug delivery, LNPs
Shipping Requirements:
Dry Ice
Appearance:
Powder
Molecular Weight:
486.4g/mol
Witika, Bwalya A., et al. "Current advances in specialised niosomal drug delivery: Manufacture, characterization and drug delivery applications." International Journal of Molecular Sciences 23.17 (2022): 9668.
Storage:
-20C
