Poly(Caprolactone-co-glycolide), 85:15, IV 1.8 dL/g
CAS Number:
N/A
Linear Formula:
(C6H10O2)m(C2H2O2)n
In stock
Poly(Caprolactone-co-glycolide) (PCLGA) is a biodegradable and biocompatible copolymer made by the copolymerization of the monomers caprolactone and glycolide. PCLGA has a wide range of potential applications in the biomedical and pharmaceutical industries including medical devices, tissue engineering, 3D printing, and controlled release implants.
The monomer ratio of PCLGA has a significant impact on the degradation rate of the material with a higher proportion of glycolide leading to more rapid degradation rate due to the glycolide having a greater degree of hydrophilicity and lower crystallinity compared to caprolactone, thus making it more susceptible to hydrolysis and enzymatic degradation.
We offer several PCLGA products of varying monomer ratios and molecular weights.
Shipping Requirements:
Dry Ice
Synonyms/Acronyms:
PCL/PGA
PCL-co-PGA
PCL and PGA Copolymer
PCLGA
Viscosity:
~1.8 dL/g [i.v.]
Appearance:
White to off-white solid
Molecular Weight:
-
Biodegradation Time:
~ Months
1. Cui, H., Sinko, P.J. The role of crystallinity on differential attachment/proliferation of osteoblasts and fibroblasts on poly (caprolactone-co-glycolide) polymeric surfaces. Front. Mater. Sci. 6, 47–59 (2012). https://doi.org/10.1007/s11706-012-0154-8
2. Zhiqiang Jiang, Yujing You, Xianmo Deng, Jianyuan Hao, Injectable hydrogels of poly(ɛ-caprolactone-co-glycolide)–poly(ethylene glycol)–poly(ɛ-caprolactone-co-glycolide) triblock copolymer aqueous solutions, Polymer, Volume 48, Issue 16, 2007, Pages 4786-4792, ISSN 0032-3861, https://doi.org/10.1016/j.polymer.2007.06.003.
Hazards:
Harmless - use normal precautions; Hygroscopic
Handling:
Gloves & fume hood
Storage:
Protect from moisture. Store at -20°C.
