Poly(trimethylene carbonate-co-D,L-lactide), 50:50, IV 0.9 dL/g
CAS Number:
N/A
Linear Formula:
(C4H6O3)m(C3H4O2)n
In stock
Poly(trimethylene carbonate-co-L-lactide) (PTMCLLA) is a biodegradable copolymer that has gained popularity in various biomedical applications, including drug delivery, tissue engineering, and wound healing. This copolymer combines the unique properties of both monomers, resulting in a material with improved rigidity, increased biodegradability, and varied degradation compared to the homopolymers.
The biodegradation rate of PTMCLLA is typically greater compared to PTMC homopolymer due to the additional sites susceptible to hydrolytic degradation. The degradation rate of PTMCLLA is also influenced by other factors such as the molecular weight, crystallinity, pH, temperature, and presence of enzymes.
Shipping Requirements:
Dry Ice
Synonyms/Acronyms:
PTMC-co-Lactide Copolymer
PTMC and Lactide Copolymer
Viscosity:
~0.9 dL/g {i.v.]
Appearance:
Light yellow to tan solid
Molecular Weight:
-
Biodegradation Time:
~ Weeks to months
1. Ma, Zhengyu, et al. "In vitro and in vivo degradation behavior of poly (trimethylene carbonate-co-d, l-lactic acid) copolymer." Regenerative biomaterials 4.4 (2017): 207-213.
https://doi.org/10.1093/rb/rbx003
2. Yang, Jian, et al. "Hydrolytic and enzymatic degradation of poly (trimethylene carbonate-co-D, L-lactide) random copolymers with shape memory behavior." European Polymer Journal 46.4 (2010): 783-791.
https://doi.org/10.1016/j.eurpolymj.2009.12.017
Hazards:
Harmless - use normal precautions; Hygroscopic
Handling:
Gloves & fume hood
Storage:
Protect from moisture. Store at -20°C.
