Resiquimod
C17H22N4O2
Resiquimod, an imidazoquinoline compound, is a TLR7/TLR8 synthetic agonist that can be used as a vaccine adjuvant to improve antigen-specific antibody production. Resiquimod is known to activate immune cells and upregulate the levels of cytokines like TNF-α, IL-6, IL-12, and IFN-α.
SYNONYMS: R 848
>98%
Wilkinson, Alexander, et al. (2018). "Lipid conjugation of TLR7 agonist Resiquimod ensures co-delivery with the liposomal Cationic Adjuvant Formulation 01 (CAF01) but does not enhance immunopotentiation compared to non-conjugated Resiquimod+ CAF01." Journal of Controlled Release 291, 1-10.