Dimethyldioctadecylammonium (Bromide Salt)
C38H80NBr
DDAB is a synthetic amphiphilic cationic lipid adjuvant that can be used to induce cell-mediated and humoral responses. DDAB forms vesicular bilayers similar to liposomes made from phospholipids. However, due to instability, it is often combined with TDB, a glycolipid with shorter fatty acid chains, that can improve the bilayer stability of the vesicle.
SYNONYMS: DDAB
Davidsen, Jesper, et al. "Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6, 6′-dibehenate)—a novel adjuvant inducing both strong CMI and antibody responses." Biochimica et Biophysica Acta (BBA)-Biomembranes 1718.1-2 (2005): 22-31.